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Metabolism v.1.0

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shvarz:
What do you mean no other Co-A?  What about fat-CoA?

8.  Well, everyone else seems silent, so I guess we can just hook up and go for it (when PY is not looking our way :) ).  One important thing that is missing from current metabolism is NADH.  Do you know what it is and what is it for?  If yes, do you think we need to implement that?

Numsgil:
fat-CoA!  Damn.

CoASAC doesn't sound as cool.

How about Acetyl ASH.  We just refer to any coenzyme A as ASH.  That still sounds cool and Acetyl ASH isn't too ahrd to remember.

Numsgil:
Yeah, I know about NADH/NAD, etc.

Since we're not modeling mitochondria in any way, we can just assume that anything that produces NADH, or FADH2 really produces the amount of ATP that would normally be produced by the mitochondria.

I don't feel bad about this level of abstraction at all.

Numsgil:
Okay, this is the beginnings of my look into photosynthesis:

The Calvin Cycle.

shvarz:
well, it is not just energy.  Here is an example from glycolisis:

you break glucose anaerobically - you get 2 ATP and 2 NADH and 2 pyruvates, so seems like you got 8 ATP (NADH = 3 ATP)

but then bacteria actually convert pyruvate to alcohol and spend these 2 NADH.  WTF?  Why do they do that?  It is because the amount of NAD is limited, so if you keep splitting glucose you run out of NAD.  Normally NADH is converted to ATP by giving H to oxygen.  But without oxygen you can't get even the 2 ATP that you were able to get before, because all your NAD is NADH.  So they have to waste 2 perfectly good NADH.

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